admin – Page 2 – Immutek Jsc

Antibody-laden nasal spray could provide COVID protection — and treatment

Scientists create a hybrid antibody that can sharply cut the amount of SARS-CoV-2 in the lungs of infected mice. Diana Kwon Antibodies swarm a SARS-CoV-2 particle (artist’s impression). A bioengineered antibody can block the virus from taking hold in the lungs of mice.Credit: KTSDesign/Science Photo Library A nasal spritz of a designer antibody offers strong protection against variants of the coronavirus SARS-CoV-2 — at least in mice1. Since the early days of the pandemic, scientists have been developing antibodies as treatments for COVID-19. [...]

1323P Natural killer cell activity as a prognostic biomarker in non-small cell lung cancer patients treated with check-point inhibitors

Background Immunotherapy has improved survival for patients with incurable non-small cell lung cancer (NSCLC). The only validated biomarker is tumour PD-L1 expression. The aim of the present study was to evaluate NK cell activity as a prognostic biomarker in patients with NSCLC treated with PD-1/PD-L1 inhibitors. Methods Enrolled patients were eligible for PD-1/PD-L1 inhibitor treatment (any line). NK cell activity was estimated using 1 ml of blood. Blood was sampled into special tubes (NK Vue® tubes) and placed in an incubator at [...]

NK cells with bispecific antibody show activity against lymphoma cells

A CD16+ NK cell (blue) bound with AFM13 (red) works to eliminate a CD30+ lymphoma cell (yellow) through interactions at the immune synapse (pink). Credit: Pinaki Banerjee, Ph.D. Cytokine-activated natural killer (NK) cells derived from donated umbilical cord blood, combined with an investigational bispecific antibody targeting CD16a and CD30 known as AFM13, displayed potent anti-tumor activity against CD30+ lymphoma cells, according to a new preclinical study from researchers at The University of Texas MD Anderson Cancer Center. The findings were published [...]

Should it be feared that immunity to Covid-19 does not last?

The decrease in antibodies in the blood is not an indication that your immune system is not resistant to the corona virus, or it is not a sign that we cannot develop vaccines for disease prevention. Over the past several months, a lot of scientific studies – with or without review – have shown that the antibody response of people infected with SARS-Cov 2 has decreased dramatically within 2 months. The press reports have raised fears that the immunity of [...]

Bí quyết dinh dưỡng dự phòng lây nhiễm COVID-19 (nCoV)

SECRETS ON NUTRITIONAL PREVENTION OF COVID-19 INFECTION (NCOV)

In addition to COVID-19 (nCoV) infection prevention measures as recommended by the Ministry of Health and the World Health Organization, ensuring adequate nutrition and maintaining an active, healthy lifestyle. plays a very important role in helping to improve immunity and prevent disease. A food-diversity diet, full and balanced with macronutrients and micronutrients that are crucial to immune system function, can help reduce risk as well as shorten duration cure. However, even for healthy people who are not yet sick, [...]

Should you try the Keto Diet?

The keto diet is touted as a miracle weight loss method, but such a diet is a medical diet with potential health risks. In a variety of weight loss diets, the high-protein low-carbohydrate diet gets a lot of attention. The Paleo, South Beach, and Atkins diets all fall into this group, and they are sometimes referred to as the keto diet. However, the keto diet in the true sense is not. Unlike low-carb diets, which only focus on protein, the [...]

Sleep and inflammation

The discovery of reciprocal connections between the central nervous system, sleep and the immune system has shown that sleep enhances immune defences and that afferent signals from immune cells promote sleep. One mechanism by which sleep is proposed to provide a survival advantage is in terms of supporting a neurally integrated immune system that might anticipate injury and infectious threats. However, in modern times, chronic social threats can drive the development of sleep disturbances in humans, which can contribute [...]

Intestinal Bacteria and Mucosal Immune system

In the intestinal tract of mammals such as humans and mice, there are billions of bacteria, viruses and fungi, collectively known as microbiota; They peacefully coexist with the intestinal mucosal immune system due to the separation by a cellular mesenteric barrier. The question is whether gut bacteria is good or bad and what it means for the health and immune system. Observations from the 60s of the last century showed that germ-free mice exhibited underdevelopment of some immune organs as [...]

NK cell-based therapeutics for lung cancer

Abstract With the development of technologies that can transform immune cells into therapeutic modalities, immunotherapy has remarkably changed the current paradigm of cancer treatment in recent years. NK cells are components of the innate immune system that act as key regulators and exhibit a potent tumor cytolytic function. Unlike T cells, NK cells exhibit tumor cytotoxicity by recognizing non-self, without deliberate immunization or activation. Currently, researchers have developed various approaches to improve the number and anti-tumor function of NK cells. [...]

Prolonged Immunoparalysis of NK Cells After Surgery.

After surgery, immune system function is impaired, which has been acknowledged by surgeons. After cancer surgery, it was found that anti-cancer ability through direct poisoning mechanism of NK cells was reduced (transiently, about 1 week). The study found that in more than 90% of patients surveyed, NK cell Interferon gamma secretion activity decreased below detection levels of this assay, and this decrease persisted up to 1 month after surgery with about 65 % of cases. phau-thuat

Author - admin